Some drugs that inhibit protein synthesis in bacteria can also be harmful to humans. Why? a. Some drugs are just so "powerful" that they inhibit human protein synthesis b. Humans and bacteria have very similar types of ribosomes c. Eukaryotic mitochondria have 70S ribosomes d. Some human cells have mutated ribosomes which are more susceptible to these drugs
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The antibiotic rifamycin is selectively toxic in blocking protein synthesis in Mycobacterium tuberculosis because Select one: a. bacterial ribosomes are 70s whereas host ribosome are 80s, thus the antibiotic binds to the M. tuberculosis ribosome but does not bind to the eukaryotic machinery. b. the drug binds to the initiator tRNA, preventing the formation of the protein synthesis initiation complex in the bacterial cell. c. the antibiotic binds to the mRNA once synthesized, preventing it from participating in the initiation complex with the ribosome. d. it binds preferentially to bacterial RNA polymerase rather than the eukaryotic protein, effectively halting transcription in the pathogen but not the host.
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