Question

Studies conducted with a lysozyme (an enzyme) mutant that contains an Asp->Asn mutation at position 52 and a Glu->Gln mutation at position 35 exhibited almost a complete loss in enzymatic activity. What is the most likely explanation for the decrease in enzyme activity in the mutant? (2 Points)

Name: studies conducted with a lysozyme an enzyme mutant that contains an asp asn mutation at position 52 and a glu gln mutation at position 35 exhibited almost a complete loss in enzymatic activi 41688
Uploaded: 2023-03-22T10:46:56-08:00
Duration: 3 min 15 s
Channel: Madhur L
Description: studies conducted with a lysozyme an enzyme mutant that contains an asp asn mutation at position 52 and a glu gln mutation at position 35 exhibited almost a complete loss in enzymatic activi 41688

          Studies conducted with a lysozyme (an enzyme) mutant that contains an Asp->Asn mutation at position 52 and a Glu->Gln mutation at position 35 exhibited almost a complete loss in enzymatic activity. What is the most likely explanation for the decrease in enzyme activity in the mutant? (2 Points)

Added by Laura H.

Biology for AP Courses

Julianne Zedalis, John Eggebrecht

Instant Answer

Solved by Expert Madhur L

03/22/2023

Step 1

Aspartic acid (Asp) is often involved in catalytic activity in enzymes, and replacing it with asparagine (Asn) may alter the structure and function of the active site, leading to a decrease in enzymatic activity. Show more…

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Studies conducted with a lysozyme (an enzyme) mutant that contains an Asp->Asn mutation at position 52 and a Glu->Gln mutation at position 35 exhibited almost a complete loss in enzymatic activity. What is the most likely explanation for the decrease in enzyme activity in the mutant? (2 Points)