00:01
Hello, students.
00:01
So today's question is that individuals with defects early in the early components of the classical complement cascade, which are c1, c2, c4, which are involved in the early stages of the classical component complement pathway.
00:17
They suffer from the autoimmune kidney disorders rather than the immunodeficiency, rather than immunodeficiency leading to increased infections.
00:27
And why is it so? why is it so? they suffer from autoimmune disorder rather than immunodeficiency.
00:37
So what is autoimmune disorder and what is immunodeficiency? we have to know these terms first of all.
00:44
So autoimmune is something when your body, your immune cells, immune cells, attack your own cells.
00:55
Attack your own cells.
01:00
So another thing is that in immunodeficiency, immunodeficiency as the name depicted, the person, if that person, so immunity is not enough to fight the infections.
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Immunity is not enough to fight the infections.
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To fight the infections.
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So in case of kidney disorders, when your early components, early components are with defect, they lead to this disease, autoimmunity, rather than immunodeficiency.
01:36
Because in kidney disorders, in kidney disorders, if you are early, there are early defects in classical pathway.
01:50
Classical pathway is that pathway, classical complement pathway, is one of the complement pathways.
01:59
Pathways, which is part of our immune system.
02:04
It is part of our immune system, immune system, and it is initiated by the antigen antibody complex.
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Initiated by antigen antibody complex.
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So when we know that the early components are the c1, c2, c4.
02:34
These are the early components.
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Even if there is some, there is some defects.
02:40
But even if it leads to some kidney disorders, there is deposition of these elements...