Ten days ago, a 12-year-old girl in sickle cell crisis was transfused with 6 units of blood over a 48-hour period. Her antibody screen and DAT were negative, and all 6 units were compatible. Her post-transfusion hemoglobin stabilized at 9.0 g/dl. She had been transfused with 2 units of pRBCs 3 years prior. At that time, her antibody screen was negative, and the transfusions were uneventful. She was readmitted to the hospital with a hgb of 4.5 g/dl, indirect bilirubin of 5.8 mg/dl, and a 4+ DAT and a positive antibody screen. Her panel results are in the content you downloaded labeled #51. It appears that this patient is experiencing a massive delayed hemolytic transfusion reaction and that she has antibody(ies) that are incompatible with the donor units. What can you determine about the antibody(ies) from the LISS, AHG, and Enzyme AHG panels?
a) There are multiple antibodies present.
b) Some antibody(ies) are destroyed by enzymes.
c) There are cold and warm antibodies present.
d) All of the above.
e) A and C.