A 60-year-old woman with anemia is admitted to the hospital. Her hematocrit is 17% and she has been experiencing subtle gastrointestinal bleeding over many weeks. Her physician requests 4 units of red blood cells for transfusion. The patient's RBCs are phenotyped as group AB, D-positive. Her antibody screen is negative on the sample drawn in the emergency room, but her records indicate a previously detected anti-E. Only three group AB, D-positive red blood cell units are available in the blood bank's inventory. The blood bank's inventory contains RBC donor units of all ABO and D types. Additional Testing: After antigen screening the 4 units of red blood cells for the E antigen, one of the group AB D-positive units is E-positive.