Below is an illustration of the 20 locations (loci) that are investigated for the number of repeating sequences (STRs) when creating a DNA profile for an individual. When looking at the TPOX locus on chromosome #2, the sequence that is found in everyone is AATG. The number of repeats found in both #2 chromosomes in the mother are 4, 6. The number of repeats found in both #2 chromosomes in the father are 7, 4.
a) So, everyone on earth has the AATG sequence at the TPOX locus on chromosome #2, but what is the difference between one person and the next?
b) Provide three examples of repeat sequences that could be found in the son or daughter?
c) Are these repeats found in coding or noncoding regions of DNA?
d) What is one basic difference between coding and noncoding regions of DNA?
D3S1358
D2S441
TH01
D12S391
D8S1179
VWA
D1S1656
D13S317
D2S1338
D7S820
D10S1248
10
11
12
13
D16S539
D18S51
D21S11
D19S433
D22S1045
14
15
16
17
18
19
20
21
22