00:01
In the not answer this question, let's talk about harding -wen equilibrium.
00:04
They are asking you calculate the frequency of...
00:06
And well, they are not giving us a specific question, but let's calculate the dominant allele frequency, the excessive frequency, and also the frequency for each of the genotypes that you can have here, okay? so, remember that according to a harding -wamer equilibrium, p plus q is equal to 1, where p is the frequency of alleys in the population that are dominant allelels, and q is the frequency of alleles in the population that we see if atlil.
00:28
You have also that p -square p -p, plus 2pq plus q square is equal to 1, where p square is the frequency of individuals in the population of the homozygous doglan, 2pq is the frequency of individuals in the population of those psychos, and qsquare is the frequency of individuals in the population of that homozygos, recessive.
00:46
So in this case, it says the ability to taste the bitter compound pdc is an auto -dominal trait.
00:53
So practically this is the ability to taste pdc and this recessive only list the inability to taste, ptc.
01:03
So it says in a sample of 500 people, so you have a total of 500 people.
01:11
It says 388 have the ability to taste ptc.
01:18
So it means that together the homocygoes dominant plus the heterocygous are going to be 388.
01:25
And it means that the remaining 112 don't have the ability to taste ptc.
01:32
It means that, they are homocybo -sessive.
01:35
So if you want to work with this information, here you have to start working with a homocybo -de -accessive.
01:42
The frequency for the homo -sidicestive is q -square.
01:45
So it means that u .s.
01:46
Square is equal to 112 divided by the total because this is a frequency, okay? this is not only a number or amount of people that don't have the ability to take pdc, it is a frequency.
01:58
So you have to divide this number by the total that is 500.
02:02
So you can use a calculator and divide 112 by 500, and you're going to get that q square is equal to 0 .224.
02:16
Now you can apply good squares, good square at both sides in order to get the value for q...