The base analog 5-bromouracil can tautomerize. One tautomer behaves like thymine and the other behaves like cytosine. If 5-bromouracil is used as a mutagen, what is the minimum number of times replication must occur to mutate the codon for proline (ccc) into the codon for serine (tcc)? Multiple choice: three generations, 5-bromouracil cannot induce this mutation, one generation, two generations.