The Big Picture: Fungi are fascinating microbes that seem to enjoy masquerading as plants. The majority of infections they cause are in individuals who are immunocompromised and unable to defend against pathogens. In some cases, fungi find ways to cause infection in healthy persons. During your examination of the topics in this chapter, consider the following: Which infections are potentially life-threatening to those without immune defenses? 2. Which fungal infections are opportunistic in healthy individuals who share public spaces? 3. In which industry are technicians required to prove licensure to operate? What type of pathogenic mutation has made treating fungal infections more difficult?
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Which infections are potentially life-threatening to those without immune defenses? The passage mentions that the majority of infections caused by the Big Picture fungi are in individuals who are immunocompromised and unable to defend against pathogens. Show more…
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Mycologist John Taylor of the University of California, Berkeley, suggests that a close biochemical relationship between fungi and animals may explain why fungal infections are typically so resistant to treatment, and why it has proven rather difficult to develop drugs that kill fungi without damaging their human or other animal hosts. Hundreds of fungal genomes have been sequenced, including those of several medically important species. If you are a researcher working to develop new antifungal drugs, how could you make use of this growing genetic understanding? Using Internet resources, can you find examples of antifungal drugs that exploit biochemical differences between animals and fungi?
One of the physicians is skeptical of your explanation for why it is challenging to find a treatment for a fungal pathogen. They state that fungi look a lot more like plants than animals. Which of the following would tell them is a key difference between plants and fungi? plants have cells with a nucleus, which is lacking in fungi plants are motile and fungi are not plants acquire energy through photosynthesis, and fungi eat other organisms plants do not have vascularized tissue like that seen in fungi
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