The conservation of primary sequence is more informative than the conservation of tertiary structure for predicting a protein’s function
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The primary sequence of a protein refers to the linear sequence of amino acids, while the tertiary structure refers to the three-dimensional shape that the protein folds into. Show more…
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The three-dimensional structure of biomolecules is more conserved evolutionarily than is sequence. Why?
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Using the same gene/protein targets, which multiple-sequence-alignment would you expect to be more informative with respect to evolutionary conservation? DNA, RNA, or Protein? (This relates to alphabet complexity and potential impacts of changes) a. Proteins, because there is more information in the 20-letter code than the degenerate DNA codon code. b. DNA, because the sequences are longer so you have more information to compare. c. RNA, because this has only the protein-coding part of genes but is three times longer than proteins. d. This is impossible to generalize.
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