The epidermis is renewed from stem cells in its basal layer. The basal layer contains a mixture of stem cells and dividing precursor cells that are produced from the stem cells. It is also known that the adhesion of integrin to the basal lamina is essential to maintain the stem cell activity there. Which of the following is true?
When bound to the basal lamina, the integrin receptor may stimulate cell proliferation.
When bound to the basal lamina, the integrin receptor may stimulate apoptosis.
When bound to the basal lamina, the integrin receptor may stimulate cell migration.
When bound to the basal lamina, the integrin receptor may weaken the desmosome.