Question

The following human pedigree shows a family affected by a specific disease. Assume that the individuals marked with an asterisk (*) do not carry any allele associated with the affected phenotype and that no other mutation spontaneously occurs. Also, assume complete penetrance Affected female Affected male Unaffected female Unaffected male 1st Pedigree a) State the most likely mode of inheritance for this disease. Choose from: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive. b) Write all possible genotypes of the following individuals in the pedigree. Use the uppercase "A" for the allele associated with the dominant phenotype and lowercase "a" for the allele associated with the recessive phenotype. Individuals | All possible Genotypes #1 | #2 | #4 | c) What is the probability that Individual #5 will be a carrier?

          The following human pedigree shows a family affected by a specific disease. Assume that the individuals marked with an asterisk (*) do not carry any allele associated with the affected phenotype and that no other mutation spontaneously occurs. Also, assume complete penetrance

Affected female
Affected male
Unaffected female
Unaffected male

1st Pedigree

a) State the most likely mode of inheritance for this disease. Choose from: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive.

b) Write all possible genotypes of the following individuals in the pedigree. Use the uppercase "A" for the allele associated with the dominant phenotype and lowercase "a" for the allele associated with the recessive phenotype.

Individuals | All possible Genotypes
#1 |
#2 |
#4 |

c) What is the probability that Individual #5 will be a carrier?

The following human pedigree shows a family affected by a specific disease. Assume that the individuals marked with an asterisk (*) do not carry any allele associated with the affected phenotype and that no other mutation spontaneously occurs. Also, assume complete penetrance

Affected female
Affected male
Unaffected female
Unaffected male

1st Pedigree

a) State the most likely mode of inheritance for this disease. Choose from: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive.

b) Write all possible genotypes of the following individuals in the pedigree. Use the uppercase "A" for the allele associated with the dominant phenotype and lowercase "a" for the allele associated with the recessive phenotype.

Individuals | All possible Genotypes
#1 |
#2 |
#4 |

c) What is the probability that Individual #5 will be a carrier?

Added by Anthony V.

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