00:06
In the pedigree, in the given pedigree, the normal allele is represented by capital a and the mutant mutant allele is represented by small a.
00:28
Now, the parent, parent in generation 1, generation 1 are, both are carriers, both are carriers which is represented by capital a small a.
00:56
When they, when these parents of generation 1 will have children, when they have children, each child, each child has a 25 percent chance of inheriting, 25 percent chance of inheriting 2 copies of the mutant, 2 copies of the mutant allele and, and being affected, 2 copies of mutant allele and being affected.
02:02
And being a carrier, being a carrier and 25 percent chance of inheriting, 25 percent chance of inheriting 2 copies of normal allele, 2 copies of mutant allele and 2 copies of normal allele as well...