The GULO gene likely became a pseudogene at position B on the phylogeny.
Added by Susan C.
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However, some species, such as humans, have lost the ability to synthesize vitamin C due to mutations in the GULO gene. Show more…
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Which of the following is the most likely effect of the mutation at nucleotide position 7 in the GULO gene of humans? A. The mutation results in the deletion of the GULO gene, so no polypeptide can be translated. B. The deletion of the single nucleotide causes a frameshift, changing the primary structure downstream of the mutation and resulting in a nonfunctional protein. C. The point mutation causes a substitution of the amino acid isoleucine (Ile) for histidine (His) at position 7, resulting in a protein with higher than normal activity. D. The substitution of a single nucleotide in the GULO coding region results in a stop codon. This results in a smaller nonfunctional protein.
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