The lac operon consists of regulatory regions such as the promoter as well as the structural genes lacZ, lacY, and lacA, which code for proteins involved in lactose metabolism. What would be the outcome of a mutation in one of the structural genes of the lac operon? a. Mutation in structural genes will stop transcription. b. Mutated lacY will produce an abnormal $\beta$ galactosidase protein. c. Mutated lacA will produce a protein that will transfer an acetyl group to $\beta$ galactosidase. d. Transcription will continue but lactose will not be metabolized properly.
Added by Jessica S.
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Step 1: A mutation in one of the structural genes of the lac operon, such as lacZ, lacY, or lacA, can affect the function of the protein coded by that gene. Show more…
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Mutations in any of the genes involved in lac operon will lead to loss of functionality. What is the effect on the operon if the lac promoter is mutated? A) RNA polymerase is unable to bind to the DNA upstream of the lac operon, and the lacZ and lacY genes are not be transcribed, even in the absence of the inducer (lactose). B) RNA polymerase is unable to bind to the DNA upstream of the lac operon, and the lacZ and lacY genes are not be transcribed, even in the presence of the inducer (lactose). C) The lacY gene will be continuously transcribed, even in the absence of the inducer (lactose). D) The lacZ gene will be continuously transcribed, even in the absence of the inducer (lactose).
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The lac operon in E. coli controls the gene expression of the enzymes that digest lactose in the cell. In the presence of lactose, the lac operon will turn on and the genes will be expressed. Place the events of gene regulation by the lac operon in order of their occurrence, from the introduction of lactose to the environment to when the cell begins to digest lactose. A. The repressor is removed from the operator. B. RNA polymerase binds to the promoter region. C. Lactose enzyme genes are expressed by the operon. D. The regulatory gene expresses the repressor protein. E. The repressor is inactivated by lactose.
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Lactose digestion in $E$ . coli begins with its hydrolysis by the enzyme $\beta$ -galactosidase. The gene encoding $\beta$ -galactosidase, lacZ, is part of a coordinately regulated operon containing other genes required for lactose utilization. Which of the following figures correctly depicts the interactions at the $lac$ operon when lactose is not being utilized?
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