00:01
Okay, so the question is, there is a mutated gene a within the species chromosome.
00:10
I'm just going to use bacteria as an example.
00:12
So the question is, how can this mutation eventually benefit the species? so if you use bacteria as an example, let's say gene a codes for a protein known as dna gyrus.
00:24
Now, dna gyrus is critical for replication, okay? without dna gyrus, dna cannot be replicated.
00:40
The cell is effectively dead.
00:44
So, there's a class of antibiotics known as fluoroquinolones.
00:54
Okay? floroquinolones.
00:56
They target dna gyrus.
00:58
So fluorokinolones will go and they will inhibit gene a.
01:02
But let's say species has a mutated gene a.
01:06
And there's a structural mutation, right? and because of this mutation, the class of antibiotics, these floral quinolones, and i think you might have heard of a particular drug, let's call, say, cypro -floxacin, sometimes called cypro, i'm sure you've heard of that, or maybe your parents have, or i'm sure you've taken, if you have taken any sort of antibiotics, you probably have taken cypro -floxacin, if you went to the doctors.
01:33
So let's say some bacteria have gene a, and they are inhibited by fluoroquinolones.
01:40
Well, let's say the same species, but some cells have this mutated gyrase a, or dna gyrase, so mutated gene a...