The local mediator nitric oxide stimulates the intracellular enzyme guanylyl cyclase by activating a G protein. activating a receptor tyrosine kinase. diffusing into cells and stimulating guanylyl cyclase directly. activating an intracellular protein kinase.
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The local mediator nitric oxide is the signaling molecule that stimulates the intracellular enzyme guanylyl cyclase. This is an example of a signaling system in which: a. The signal molecule first diffuses through the membrane before binding its target receptor inside the cell. b. The signal molecule first binds to and then activates a receptor tyrosine kinase on the cell surface. c. The signaling molecule first binds to a G-protein coupled receptor (GPCR) on the cell surface. d. The signal molecule first diffuses through the membrane before activating an intracellular protein kinase inside the cell.
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The direct effect of cAMP in the protein kinase A pathway is to: A. Activate adenylyl cyclase B. Dissociate the regulatory subunits from the catalytic subunits of PKA. C. Phosphorylate Src-containing proteins D. Phosphorylate protein kinase A.
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Protein phosphorylation is commonly involved with which of the following? (A) ligand binding by receptor tyrosine kinases. (B) activation of G protein-coupled receptors. (C) activation of protein kinase molecules. (D) release of $\mathrm{Ca}^{2+}$ from the ER lumen.
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