Question

1. The microtubule network plays a critical role in controlling the spatial distribution of organelles within the cell. The distribution of the microtubule network within a cell is itself regulated by three factors: (1) the microtubule-organizing center (MTOC; centrioles), (2) dynamic instability, and (3) capping proteins. a. Why do microtubules grow from the MTOC rather than polymerizing spontaneously at random locations in the cell? 2. Two investigators are examining the kinesin- and dynein- driven movement of organelles along microtubules. They notice that most of the time organelles moving along the same microtubule in opposite directions can pass by each other. However, they also notice that occasionally these organelles cannot pass one another. After many observations of individual passing events, they calculate that the organelles cannot pass each other 7.7% of the time. From this observation, what do they conclude about how dynein and kinesin walk along microtubules?

          1. The microtubule network plays a critical role in controlling the spatial distribution of organelles within the cell. The distribution of the microtubule network within a cell is itself regulated by three factors: (1) the microtubule-organizing center (MTOC; centrioles), (2) dynamic instability, and (3) capping proteins.

a. Why do microtubules grow from the MTOC rather than polymerizing spontaneously at random locations in the cell?

2. Two investigators are examining the kinesin- and dynein- driven movement of organelles along microtubules. They notice that most of the time organelles moving along the same microtubule in opposite directions can pass by each other. However, they also notice that occasionally these organelles cannot pass one another. After many observations of individual passing events, they calculate that the organelles cannot pass each other 7.7% of the time. From this observation, what do they conclude about how dynein and kinesin walk along microtubules?

1. The microtubule network plays a critical role in controlling the spatial distribution of organelles within the cell. The distribution of the microtubule network within a cell is itself regulated by three factors: (1) the microtubule-organizing center (MTOC; centrioles), (2) dynamic instability, and (3) capping proteins.

a. Why do microtubules grow from the MTOC rather than polymerizing spontaneously at random locations in the cell?

2. Two investigators are examining the kinesin- and dynein- driven movement of organelles along microtubules. They notice that most of the time organelles moving along the same microtubule in opposite directions can pass by each other. However, they also notice that occasionally these organelles cannot pass one another. After many observations of individual passing events, they calculate that the organelles cannot pass each other 7.7% of the time. From this observation, what do they conclude about how dynein and kinesin walk along microtubules?

Added by Stephanie C.

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