The scientist wanted to use antibody B clinically (to treat humans), but this proposal was rejected. Which of the following is the most logical reason for the rejection? B. Because the antibody was generated in the mouse, repeated usage in the same patient would elicit the production of human anti-mouse antibodies. C. Because the antibody was generated in the mouse, it will not recognize human antigens.
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In order to be effective, the antibody must recognize and bind to specific human antigens. Option B suggests that the rejection is due to the production of human anti-mouse antibodies after repeated usage. This is a valid concern, as the human immune system may Show more…
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