Question

The series of steps in beta oxidation that are similar from succinate onward in the TCA cycle involve: fatty-acyl-CoA oxidation, hydration, oxidation, and thiolysis fatty-acyl-CoA oxidation, dehydration, oxidation, and thiolysis fatty-acyl-CoA dehydration, oxidation, and thiolysis fatty-acyl-CoA hydration, oxidation, and thiolysis In order to transport free fatty acids into the mitochondrion for beta-oxidation, what has to happen to the fatty acid for transport to occur? The fatty acid must be initially broken down by beta oxidation in the cytosol to generate acetyl-CoA - only acetyl-CoA can enter the mitochondrion. The fatty acid must be converted into a fatty acyl CoA by a reaction that requires ATP and free coenzyme A catalyzed by acyl-CoA synthetase. The fatty acyl-CoA must be converted into a fatty acyl carnitine, a reaction catalyzed by carnitine acyl-transferase 1. Both answers 2 and 3.

          The series of steps in beta oxidation that are similar from succinate onward in the TCA cycle involve:
fatty-acyl-CoA oxidation, hydration, oxidation, and thiolysis
fatty-acyl-CoA oxidation, dehydration, oxidation, and thiolysis
fatty-acyl-CoA dehydration, oxidation, and thiolysis
fatty-acyl-CoA hydration, oxidation, and thiolysis
In order to transport free fatty acids into the mitochondrion for beta-oxidation, what has to happen to the fatty acid for transport to occur?
The fatty acid must be initially broken down by beta oxidation in the cytosol to generate acetyl-CoA - only acetyl-CoA can enter the mitochondrion.
The fatty acid must be converted into a fatty acyl CoA by a reaction that requires ATP and free coenzyme A catalyzed by acyl-CoA synthetase.
The fatty acyl-CoA must be converted into a fatty acyl carnitine, a reaction catalyzed by carnitine acyl-transferase 1.
Both answers 2 and 3.

Added by Timothy L.

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