The step from -60 to -5 on the top graph represents the clamped voltage, and the bottom graph represents the current through the sodium channel. You can compare to the control and capsaicin effect by clicking on those buttons on the computer screen. What do these graphs tell us about the action of Lidocaine? a) Lidocaine opens potassium channels from outside the cell b) Lidocaine inhibits the voltage-gated sodium channels c) Lidocaine activates the TRPV1 channel d) Lidocaine triggers an action potential
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The top graph shows the clamped voltage from -60 to -5, indicating a change in membrane potential. The bottom graph shows the current through the sodium channel, which is crucial for understanding the effect of Lidocaine. Show more…
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