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A receptor antagonist is used to prevent the events that occur downstream of a receptor, elicit a response by binding to a receptor, prevent a response by binding to a receptor, or increase a response by binding to a receptor. Regulation of metabolic pathways most typically occurs at enzyme steps that are thermodynamically reversible and internal to the pathway, or thermodynamically irreversible and at the beginning or end of the pathway. Which of the following is an allosteric inhibitor of glycolysis? F2,6 BP F1,6 BP AMP ATP What is the primary outcome of the malate-aspartate shuttle run during glycolysis? Movement of electrons (equivalents) from the cytosol to the mitochondrial matrix Movement of malate from the mitochondrial matrix to the cytosol Movement of malate from the cytosol to the mitochondrial matrix Movement of electrons (equivalents) from the mitochondrial matrix to the cytosol Which statement is FALSE about Complex III of the electron transport chain? It receives electrons from Coenzyme Q. It transfers electrons to cytochrome C. It results in the movement of 4 protons across the mitochondrial membrane. It receives electrons from succinate.
Madhur L.
Receptors perform the following function/functions: Ligand recognition, Signal transduction, Both ligand recognition and signal transduction, Disposal of agonists and antagonists. The following receptor has an intrinsic ion channel: Histamine H1 receptor, Histamine H2 receptor, Adrenergic alfa receptor, GABA-benzodiazepine receptor. 16. Select the receptor that is located intracellularly: Opioid ÎĽ receptor, Steroid receptor, Prostaglandin receptor, Angiotensin receptor. All of the following serve as intracellular second messengers in receptor mediated signal transduction except: Cyclic AMP, Inositol trisphosphate, Diacyl glycerols, G proteins. Down regulation of receptors can occur as a consequence of: Continuous use of agonists, Continuous use of antagonists, Chronic use of CNS depressants, Denervation.
QUESTION 6 The key aspect of receptor gating in the associative induction of hippocampal LTP is that a. all glutamate receptors open automatically whenever glutamate is in the synaptic cleft. b. the NMDA receptor acts as a molecular coincidence detector. c. the AMPA receptor allows calcium into the cell only after the NMDA receptor is activated. d. both the NMDA and AMPA channels must be open in order for the cell to depolarize. e. All of the above are key aspects of LTP induction. QUESTION 7 NMDA receptor activation requires: a. Depolarization of the postsynaptic neuron. b. The presence of AMPA receptors. c. Removal of a Mg++ ion from the NMDA receptor pore. d. Glycine. e. All of the above. QUESTION 8 Silent synapses are silent because they a. have no presynaptic terminal. b. have AMPA receptors but no NMDA receptors. c. have NMDA receptors but no AMPA receptors. d. lack voltage-gated sodium channels. e. are continuously inhibited and so cannot be activated.
Md.Daniyal A.
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