They can be interchanged either via rotation or reflection. All four protons can be interchanged via rotation, so all four protons are homotopic. All four protons can be interchanged via reflection, so all four protons are homotopic. None of the above.
Added by Alexander B.
Step 1
- Two nuclei (protons) are homotopic if there exists a symmetry operation of the molecule (a rotation, reflection, inversion, etc.) that maps one nucleus onto the other. Show more…
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