Tools of Genetics Part 4: Karyotype (5pt)
When cells are dividing during Mitosis, the chromosomes can be photographed and then sorted by size and arranged in homologous pairs, This arrangement is known as a Karyotype. Humans inherit 23 chromosomes from each parent in the gametes, egg and sperm, to total 46 chromosomes in each human cell. Karyotypes provide visual evidence that a developing fetus has the correct total number of chromosomes and that each chromosome present is structurally correct. In some cases we have visible evidence, known as markers, to identify the presence of a gene causing a genetic disorder. Karyotypes can also be used to determine the gender of an individual by looking at the last pair of homologous chromosomes. If the two chromosomes are identical in size then they referred to as two "X" chromosomes and it is a girl. If the two chromosomes are different in size, one larger and one smaller, then the chromosome pair is referred to as "XY" and the gender is identified as male. These chromosomes are not the only factors that genetically determine all of the qualities of gender and we continue to learn more as our technology progresses.