Transcriptionally active chromatin tends to: O be deficient in histone H1. O All of these answer choices are true for transcriptionally active chromatin. O be devoid of nucleosomes. O contain sites hypersensitive to in vitro treatment with DNase I.
Added by Sarah B.
Close
Step 1
This accessibility is achieved through changes in chromatin structure, such as histone modification and nucleosome remodeling. Show more…
Show all steps
Your feedback will help us improve your experience
Josee Pacheco and 51 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
1.) All histones undergo post-translational modification of specific amino acids. These modifications: A. alter the charge of the histone molecule. B. are permanent. C. occur (in part) on the N-terminal arms of the histones, which are thought to extend out from the core. D. occur at specific times during the cell cycle. 2.) DNase I hypersensitive sites: A. are approximately 100-fold more sensitive to digestion than normal chromatin. B. Are regions where the DNA is free of nucleosomes. C. Are regions where the DNA is free of proteins. D. usually occur only when a gene is being expressed. E. Can be found at promoters, origins of DNA replication, and centromeres. F. Can be maintained through DNA replication. 7) When a gene is active: A. the promoter is generally free of nucleosomes. B. The entire gene is generally free of nucleosomes. C. The gene is covered by nucleosomes, but the chromatin structure is altered in such a way that the entire gene is more sensitive to nuclease degradation. 8.) Which of the following statements about heterochromatin is true? A. It is transcriptionally inactive. B. It remains condensed during interphase when active chromatin decondenses. C. Constitutive heterochromatin is found in specialized parts of the chromosome that are never expressed, such as centromeres and telomeres. D. Facultative heterochromatin can control gene expression by placing genes in an inaccessible chromatin structure.
Josee P.
Histones are highly conserved across eukaryotes. Which one of the following is NOT consistent with and supportive of this observation? A) Histone variants are particular to some cell types and cell functions. B) All histones have the same general functions—to condense DNA and regulate access to it. C) DNA is composed of the same chemicals in all organisms. D) Histones are rich in arginine and lysine. The amino acid K9 of histone H3 is acetylated in the nucleosomes found in one region of chromatin. The gene or genes in this region of chromatin are more likely to be A) Transcriptionally inactive B) Insensitive to in vitro treatment with DNaseI C) Transcriptionally active D) Found outside the nucleus E) Cut with the restriction enzymes present in the nucleus
Adi S.
There is a growing body of evidence that acetylation of histone N-termini in specific chromosomal regions contributes to gene control by regulating the binding of histones to DNA and the regulation of the folding state of chromatin. The extent of histone acetylation is correlated with the relative resistance of chromatin DNA to digestion by nucleases. Explain which combination of histone acetylation state and DNase 1 resistance is characteristic of actively transcribed regions of chromatin? a) Little or no histone acetylation, highly resistant to DNase 1 b) Little or no histone acetylation, highly sensitive to DNase 1 c) High level of histone acetylation, highly resistant to DNase 1 d) High level of histone acetylation, highly sensitive to DNase 1
Suman K.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
18,000,000+
Students on Numerade
Trusted by students at 8,000+ universities
Watch the video solution with this free unlock.
EMAIL
PASSWORD