00:01
We are looking at our mrna sequences here and some mutation, mutated sequences, and trying to figure out not only what the mrna sequences are, but the possible mutations that occur from that.
00:17
So essentially i'm using this codon chart over here and translating these mrna sequences, and then we'll talk about the mutations that have occurred.
00:26
So first thing i noticed in this mutated stream, here are these differences from the original.
00:35
Most of these happen to be substitutions, or in the case of the second amino acid here, we have a complete substitution of every nucleotide.
00:54
There.
00:56
But as we can see, while there are some, this is a nonsense mutation and the fact that it doesn't occur with the original sequence as intended with amino acids, because of the redundancy of the codons for the amino acids they pair up with, we did end up with quite a few of the codons that did code for the appropriate amino acid.
01:21
I'm looking at our second mutated strand here.
01:24
There's our one singular substitution, but in this case, it probably does the most amount of damage because that substitution causes what we know as a stop codon.
01:38
So this essentially stops the production, halts the production of these amino acids, and so we end this strand very, very short...