Under starvation conditions, organisms use proteins and amino acids as sources of energy. Deamination of amino acids produces carbon skeletons that enter the glycolytic pathway and the citric acid cycle to produce energy in the form of ATP. Nucleotides are not similarly degraded for use as energy-yielding fuels. What observations about cellular physiology support this statement? DNA synthesis prevents nucleotide use in energy generation. Nucleotides are not stored for use as fuel. Organisms hydrolyze nucleotides and recover the bases, rather than completely degrading them. Nucleotide triphosphate metabolism is not reversible
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Under starvation conditions, organisms deaminate amino acids to produce carbon skeletons that can enter metabolic pathways like glycolysis and the citric acid cycle, leading to ATP production. Show more…
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Under starvation conditions, organisms can use proteins and amino acids as sources of energy. Deamination of amino acids produces carbon skeletons that can enter the glycolytic pathway and the citric acid cycle to produce energy in the form of ATP. Nucleotides are not similarly degraded for use as energyyielding fuels. What observations about cellular physiology support this statement? What aspect of the structure of nucleotides makes them a relatively poor source of energy?
Muhammad A.
Nucleotides as Poor Sources of Energy Under starvation conditions, organisms can use proteins and amino acids as sources of energy. Deamination of amino acids produces carbon skeletons that can enter the glycolytic pathway and the citric acid cycle to produce energy in the form of ATP. Nucleotides are not similarly degraded for use as energyyielding fuels. What observations about cellular physiology support this statement? What aspect of the structure of nucleotides makes them a relatively poor source of energy?
Under starvation conditions, cells deaminate amino acids to produce carbon skeletons that enter the glycolytic pathway and the citric acid cycle to generate ATP. Nucleotides, on the other hand, are not broken down to yield energy. Select the statements that describe how cells metabolize nucleotides. Although nucleotides can be hydrolyzed to release purine or pyrimidine bases, most organisms lack the enzymes to further degrade the free bases. Instead, free purine and pyrimidine bases are secreted into the bloodstream. Nucleotides are hydrolyzed into ribose and nitrogenous bases. Purines are further metabolized to uric acid and pyrimidine degradation produces urea. Free bases from hydrolysis of nucleotides are further degraded into their amino acid precursors, glycine and aspartate. Free bases released from nucleotide degradation are often reused for nucleotide synthesis. Purine and pyrimidine bases released from hydrolysis of nucleotides are used in de novo synthesis of nucleotides.
Adi S.
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