A nerve cell with normal levels of intracellular calcium is treated with intracellular IP3, which opens calcium channels in the endoplasmic re7culum. What would the transmembrane voltage across the plasma membrane of the cell (that is, the voltage of the cytoplasm rela7ve to the extracellular solu7on bathing the cell) likely be if this occurs and calcium has no other effects on the cell? A. -120 mV B. -100 mV C. -60 mV D. -30 mV E. +90 mv
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IP3 opening Ca2+ channels on the endoplasmic reticulum releases Ca2+ from the ER into the cytosol. The problem states that Ca2+ has no other effects on the cell and does not directly alter membrane permeability or ion gradients. Show more…
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