00:01
Hello students, the question says that a 60 -year -old woman with a history of rheumatoid arthritis smoking six packs per year, chronic obstructive pulmonary disease, and treated hypertension underwent a screening colonoscopy and then felt unwell for a week.
00:23
She saw her family physician, who referred her to a local hospital clinic, where they conducted the tests listed in the, where they conduct certain tests.
00:35
Now the question asked is, first one is that, what disease state is the most likely explanation for patient's laboratory results? so the most likely explanation for patient's laboratory results is an autoimmune or chronic inflammatory disease such as rheumatoid arthritis.
01:26
And the patient has a history of rheumatoid arthritis, which is known to cause polyclonal hypergammaglobulinemia.
01:57
Additionally, other medical conditions like smoking, copd, and hypertension would contribute to chronic inflammatory stage.
02:12
Another question asked is, what is the significance of polyhypergammaglobulinemia with no monoclonal immunoglobulin spike identified on spe? the significance of the polyclonal hypergammaglobulinemia with no monoclonal immunoglobulin spike identified on spe is that it suggests a non -malignant cause for the elevated immunoglobulins.
03:26
And the polyhypergammaglobulinemia is typically seen in autoimmune or chronic inflammatory diseases, where monoclonal spike would be more indicative of plasma cell disorder such as multiple myeloma.
04:25
Another question asked is, is the patient's urine protein normal? so here in this question, there is no specific value mentioned...