00:01
Okay, this question here says the figure below illustrates a metabolic pathway for coloring mice.
00:07
Aguri is dominant to black or non -aguri hair, which results from the homozygous expression of agressive mutation.
00:14
It says, when agressive mutation b at a separate locus is homozygous, it eliminates pigmentation, altogether yielding albino mice.
00:22
So you have here the precursor molecule, gene b product, black pigment, the gene a product, and the aguri pigment.
00:29
So in this case, practically, in order to express either black or aguri, you need the dominant b.
00:38
If you have the homozygous agressive b, it doesn't matter what you have here because you're going to have directly albino mice.
00:46
So it says, if you cross, or well, i'm going to just make it like this so you can understand better.
00:52
The homozygous dominant for a, or the heterozygous for a, is going to lead to aguri.
00:58
And the homozygous agressive for a is going to lead to black or non -aguri.
01:04
But this is only going to happen if you have either the homozygous dominant or the heterozygous genotype for b.
01:11
If you have directly the homozygous agressive, then you're going to get albino.
01:16
It doesn't matter what you have at this gene, or at this locus.
01:20
So the first question says, if you cross a true breeding albino mouse, true breeding means homozygous.
01:25
So if you have albino, it is like this.
01:29
And in this case, you don't know if it is homozygous agressive or homozygous dominant.
01:34
So let's leave it like this.
01:36
With a true breeding aguri mouse, so aguri is homozygous dominant for a and homozygous dominant for b because it is true breeding, it means homozygous...