Compare lipid-soluble and water-soluble hormones in terms of: what each consist of, their sources, utilization of secretory vehicles, blood transport, half-life, receptor locations, and mechanism of action.
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Compare and contrast the modes of action of lipid-soluble and water-soluble hormones.
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On the basis of their physical properties, hormones fall into one of two categories: those that are very soluble in water but relatively insoluble in lipids (e.g., epinephrine) and those that are relatively insoluble in water but highly soluble in lipids (e.g., steroid hormones). In their role as regulators of cellular activity, most water-soluble hormones do not enter their target cells. The lipid-soluble hormones, by contrast, do enter their target cells and ultimately act in the nucleus. What is the correlation between solubility, the location of receptors, and the mode of action of these two classes of hormones?
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