Drugs that target the plasma membrane are able to do so...

Name: drugs that target the plasma membrane are able to do so because select one a they target the phosphate group on the phospholipids breaking down the bilayer b they contain a lipid par 65933
Uploaded: 2023-04-26T06:39:34-08:00
Duration: 6 min 57 s
Channel: Sri K
Description: drugs that target the plasma membrane are able to do so because select one a they target the phosphate group on the phospholipids breaking down the bilayer b they contain a lipid par 65933

Drugs that target the plasma membrane are able to do so because _______. Select one: a. they target the phosphate group on the phospholipids, breaking down the bilayer b. they contain a lipid part that enables them to act as a detergent c. they are able to denature the membrane-associated proteins, creating pores thereby disrupting the integrity d. they act as enzymes to break down the phospholipids

Transcript

00:01 So we have a question about detergents.

00:06 There is a statement given and four options that we have to choose from.

00:16 First let's study about the detergent.

00:22 The statement given is that detergents can be used to remove proteins from the plasma membrane.

00:28 If the plasma membrane, we have some proteins in the plasma membrane, we have some more proteins in the plasma membrane.

00:46 So this protein which passes through the entire thickness of the plasma membrane, this is known as integral protein.

00:52 And this protein which doesn't pass through the entire thickness of the plasma membrane, we call it as peripheral protein.

01:09 So talking about the structure of the detergent, detergent also have the structure, they have a head and one or more tails.

01:19 I am drawing only two of them, you can draw even more.

01:22 One or more than one tails.

01:25 This is head part and this is tail part of the detergent.

01:33 Head is polar, water soluble.

01:39 Tail is non -polar and fat soluble.

01:45 So talking about the mechanism of action of detergent, detergents basically help in the interaction of lipid with polar substances such as water.

02:18 Basically talking about the plasma membrane, we have its structure as lipid bilayer.

02:24 So basically what do the detergents do? they help in the releasing of the peripheral proteins from the plasma membrane.

02:33 They help in the lysis of the membrane basically.

02:36 This is the plasma membrane.

02:38 Here also the structure consists of hydrophobic tail and polar head.

02:44 The detergents react with these molecules, they do not undergo chemical reaction but physical reaction with these molecules.

02:53 The tail of the detergent it basically adheres with the tail of the phospholipid bilayer and the head of the detergent it basically interacts with the head of the phospholipid bilayer and cause its disintegration.

03:14 And because of the disintegration of the plasma membrane, this leads to the release of proteins.

03:25 It's that simple.

03:27 Now let's study the options...

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