How to do recombination frequency step by step for my genetics exam
Added by Jerry P.
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It is calculated as the number of recombinant offspring divided by the total number of offspring. Show more…
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II. Recombination mapping: Explain how the map distance between two linked genes is calculated (it might be helpful to make up a data set to demonstrate how it is done). Explain why linkage is a violation of Mendel's first but not second law based on how Meiosis works and where in meiosis crossing over happens. Explain why the maximum expected recombination frequency observed is 50% for both linked and unlinked genes. For the following problem, identify the parental and double recombinant classes, as well as the dominant and recessive alleles. Find the gene order and draw a map (make sure you explain if adjustment is needed). Two strains of mice were crossed to each other. The F1 were crossed back to blue skinny short mice. The F2 were: 464 red skinny tall, 25 red fat tall, 10 red skinny short, 1 red fat short, 2 blue skinny tall, 9 blue fat tall, 24 blue skinny short, 465 blue fat short.
Adi S.
What is the recombination frequency in this case?
Genetic Mapping You read in literature that three loci are arranged as follows on a chromosome: A 25cM Q 16 cM D The coefficient of coincidence is 0.5. You decide to do a cross and cross true breeding AQd with true breeding aqD. You do a testcross with the F1. a. Give a possible symbolic representation of the F1 cross. b. Calculate what % of the offspring you would expect to find in each phenotypic class.
Josee P.
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