In the last step of the Krebs cycle, malate is converted to oxalacetate. Suppose the enzyme that catalysed this reaction was mutated so that it did not function. What would be the effect? Group of answer choices The cell would run out of oxalacetate but the Krebs cycle would continue Acetyl-CoA would react with malate (instead of oxaloacetate) to form citrate and the Krebs cycle would produce the normal amounts of NADH and FADH2 none of the other choices is correct oxalacetete would be produced from glucose and the Krebs cycle would continue to operate The cell would quickly run out of oxaloacetate and the Krebs cycle would stop
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Adi S.
Suppose the cell is metabolizing glucose under aerobic conditions, but there is a small problem in the cell and the enzyme in reaction 8 of Krebs' cycle is blocked. Answer the following questions about this problem that has occurred in the cell. Would reaction 8 still occur? Yes or No. No; because it's blocked. Would the Krebs' cycle still be able to operate? Yes or No. Explain: No; it would not be able to operate without reaction 8. Would this affect the production of NADH? Yes or No. Explain. Yes; because the enzyme would not use NAD+, so NADH would not be produced. Would this affect the production of FADH2? Yes or No. Explain. No, the production of FADH2 occurs before reaction 8. Would this affect the electron transport chain? Yes or No. Explain. Yes. How would this affect the total production of ATP under aerobic conditions in the cell? How much ATP will be produced from this glucose molecule? How much ATP will be yielded from this molecule? Explain.
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