00:01
So you're going to use the word bank from the left to fill in all the blanks.
00:04
The first one, the t cell maturation, this occurs in the first blank, thymus.
00:16
The second blank is regarding the b cell maturation.
00:21
And this occurs in the structure called bone marrow.
00:27
So second blank.
00:29
And then they develop their specificity to a single antigen.
00:34
The specificity of both b and t cell is made possible through the process of what we call genetic rearrangement.
01:06
What we call this genetic rearrangement is involved in the dna level.
01:14
That means the gene that code for b and t cell specific receptor, they actually go through a recombination.
01:20
So this is why we call this genetic rearrangement.
01:24
It happens in a dna level.
01:25
So now let's look at a second paragraph.
01:29
This talks about the specificity of the bnp cell receptor.
01:33
And they are the genes in code for the receptor are cut and spliced during, as we just mentioned, the genetic rearrangement process where the genes are randomly cut and spliced.
01:47
So since the rearrangement has been used already after i brought through the world i believe the most suitable word that can fill into this blank without being redundant is going to be the maturation process of both cells.
02:08
So b cell and t cell receptor genes are cut and spliced.
02:24
And so the most precise description is called the recombination, but the recombination is not showing up in a word bank.
02:35
And we have already used the word of rearrangement.
02:38
So the word that can fill into the blank without using the rearrangement again is going to be during maturation process.
02:52
Process.
02:57
And the actual, the more precise way is called the rearrangement or recombinant process.
03:12
So if you are allowed to use those words for more than once, then you can just say rearrangement process.
03:18
And this process occurs at the level of the dna.
03:29
So the blank here is going to be the level of gene which means that it's going to be on the the dna level rather than rna following the the next blank is going to be in the level of uh rather than the rna following this process is what we call transcription so according to the meaning of of this paragraph, it means that the genetic rearrangement occurs in the dna level, which is prior to the rna.
04:11
Dna convert to rna is called, the process is called transcription.
04:16
So this is why the last link here is transcription.
04:20
So this emphasized that the rearrangement occurs at the level of the dna rather than in rna following the process of transcription where the dna is being converted into rna.
04:33
So the third blank suggests that the blank must be the transcription where dna is being converted into rna.
04:43
Now let's move on to the third paragraph.
04:49
So b cell receptors, what are these receptors? so they are actually immunoglobulin.
05:08
So this is the first blank.
05:10
And then they are made of four, and the next blank is polypeptide...