Nuclear imports require hydrolysis of GTP, which is triggered by an accessory protein called A) Rho B) Rac C) Ran D) Rab
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Nuclear import involves the transport of proteins and other molecules into the nucleus through the nuclear pore complex. Show more…
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Once the nuclear import receptor is in the nucleus, it must be delivered to the cytosol, this process requires ...... ....... Select one: a. ATP binding protein Rab b. GTP binding protein Rab c. GTP binding protein Ran d. ATP binding protein Ran
Sri K.
GTP hydrolysis by Ran occurs in the cytosol. Based on this statement, which of the following below is true? A) Ran-GEF (guanine nucleotide exchange factor) is only found in the nucleus, from where it will promote binding of the nuclear import receptor to the cargo (a prospective nuclear protein). B) Ran-GAP (GTPase activating protein) is only found in the cytosol, from where it will promote binding of the nuclear import receptor to the cargo (a prospective nuclear protein). C) Ran-GAP (GTPase activating protein) is only found in the nucleus, from where it will promote binding of the nuclear import receptor to the cargo (a prospective nuclear protein). D) Ran-GEF (guanine nucleotide exchange factor) is only found in the cytosol, from where it will promote binding of the nuclear import receptor to the cargo (a prospective nuclear protein).
Shaiju T.
Which of the following occurs because Ran-GEF is found in the nucleus? a) Ran binds a molecule of GTP (releasing GDP), and binds the nuclear import receptor b) Ran binds a molecule of GTP (releasing GDP), which releases its binding to the nuclear import receptor c) Ran binds a molecule of GDP (releasing GTP), and binds the nuclear import receptor d) Ran binds a molecule of GDP (releasing GTP), which releases its binding to the nuclear import receptor
Arun B.
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