00:01
Hemoglobin which is written as hv.
00:03
The hemoglobin is a molecule which is popularly known as the oxygen carrier.
00:09
And this molecule is the one which will be present in the red blood cells written as rbases.
00:14
And this molecule in turn will carry oxygen and deliver it to the cells.
00:19
Besides being bound to hemoglobin, the oxygen can also be dissolved in the blood plasma.
00:27
This one, this blood plasma oxygen, is called as the partial pressure of oxygen, whereas the one which is being bound to the hemoglobin molecule, it is called as the saturation, that is the saturation of oxygen.
00:42
And these two components will determine how much of oxygen is delivered to a particular tissue.
00:47
The saturation is always greater when compared to the partial pressure of oxygen.
00:52
And it should be noted as this hemoglobin molecule has four units, that is, it contains two alpha units and two beta units.
01:00
Units.
01:01
The binding to one more one unit will determine the effects of binding to four other component of the hemoglobin molecule.
01:09
And this rbcs also have another molecule that is called as 2 comma 3 bisphosphoryg, which is written as 2 .3 pbg.
01:20
This is the molecule which is produced as a part of glycolysis and this also will be available in the red blood blood cells.
01:27
So when this red when they are also present in the red blood cells they influence the affinity with which oxygen molecule is bound to hemoglobin here o2 denotes oxygen so there naturally the oxygen affinity towards hemoglobin is actually less but when this molecule is present in the environment it still more decreases affinity for hemoglobin so let's see each of the sub questions in detail the sub question a discusses about if the levels of pbg is being right what would happen to the oxygen binding curve.
02:02
So let's say this to be the oxygen binding curve and this to be the partial pressure of oxygen which is written as pp and this to be the saturation of oxygen return as sat.
02:12
So this curve will assume a s shaped.
02:17
So when the levels of pbg tends to rise, the curve in turn will shift towards the right direction, meaning that the oxygen is unloaded very tremendously...