The frequency of nucleotide misincorporation, finc , is the ratio of efficiency of incorrect nucleotide incorporation to the efficiency of correct nucleotide incorporation. Determine the finc for each incorrect nucleotide.
Added by Linda R.
Step 1
Let's think step by step. Show more…
Show all steps
Your feedback will help us improve your experience
Adi S and 101 other Biology educators are ready to help you.
Ask a new question
Labs
Want to see this concept in action?
Explore this concept interactively to see how it behaves as you change inputs.
Key Concepts
Recommended Videos
Which of the following equations is INCORRECT with respect to the frequencies of nucleotides in double-stranded DNA? (%A + %C)/(%G + %T) = 1 100% - %G - %C - %A - %T = 0 %G + %C = %A + %T %G + %T = %C + %A (%C / %T) = (%G / %A)
Adi S.
Below is a figure comparing CTP on the left and CMP on the right. Based on these structures, and your understanding, which statement(s) below is/are CORRECT? [Choose all that apply.] Both CTP and CMP may be incorporated into a growing DNA strand by DNA polymerase. Assuming a C was matched incorrectly to an A, the proofreading function of DNA polymerase would release a CMP as a product. Assuming a C was matched incorrectly to an A, the proofreading function of DNA polymerase would release a CTP as a product. Only CMP may be incorporated into a growing DNA strand by DNA polymerase. Only CTP may be incorporated into a growing DNA strand by DNA polymerase.
Madhur L.
On average, errors occur in DNA synthesis only once in every ten billion nucleotides incorporated. Which of the following does NOT contribute to this high fidelity of DNA synthesis? A. Complementary base-pairing between the nucleotides B. "Tightening" of the DNA polymerase enzyme around its active site to ensure correct pairing before monomer incorporation C. Exonucleolytic proofreading by the 3'-to-5' exonuclease activity of the enzyme to correct mispairing even after monomer incorporation D. A strand-directed mismatch repair system that detects and resolves mismatches soon after DNA replication E. All of the above mechanisms DO contribute to the fidelity.
Josee P.
Recommended Textbooks
Biology for AP Courses
Objective Biology for NEET
Introduction to General, Organic and Biochemistry
Transcript
18,000,000+
Students on Numerade
Trusted by students at 8,000+ universities
Watch the video solution with this free unlock.
EMAIL
PASSWORD
