00:01
Hello everyone, in this question we have been asked about the role of the arrestin in the process of hormonal signaling.
00:07
So, there is this arrestin receptor complex that acts as the scaffold facilitating branches of the signaling that is the rap m e k e r k cascade and also pre -arrestin are present in the cytoplasm that acts as the scaffold that facilitates the signaling independent of the gpcr.
00:33
So, arrestins interact with other classes of membrane receptors and serve as the ubiquitous signaling regulators in the cytoplasm and nucleus like when it binds to the gpcr, the gpcr are removed from the cell membrane and it undergoes the recycling process.
00:55
So, this with the process of endocytosis will be taken in by the endosome and if it needs to be destroyed then the endosome will fuse with the lysosome and if it needs to be recycled then it and then this endosome will fuse with the plasma membrane.
01:13
So, here our right answer will be option c that is the arrestin recognizes the phosphorylated domains of the constitutively activated receptor and then promotes the receptor being endocytosized.
01:29
Then in the next question we have been asked that cytochromes are proteins using dash as the prosthetic group.
01:36
So, there is cytochrome oxidase that is known as the complex 4 in the electron transport chain and that is the heme here acts as the prosthetic group.
01:48
So, here our right answer will be option d that is heme.
01:55
Then in the next question we have been asked that what is the cellular function of glut1 protein.
02:02
So, this glut1 is basically a transmembrane protein that is responsible for the facilitated diffusion of glucose across the membrane.
02:13
So, here our answer will be option d that it here is the glucose permease.
02:21
Then the next question says that this here is the fourth question and this here is the third question.
02:27
In the third question it says where are the h plus ions concentrated during the electron movement through the electron transport chain.
02:35
So, basically the electron transport chain takes place in the mitochondria and the complexes pumps the proton from the matrix into the intermembranous space.
02:45
So, it is in the intermembranous space where the acidic ph is maintained and here only the protons are collected.
02:53
So, here our right answer is option a.
02:55
Then in the next question it says that do mitochondria have ribosomes.
02:59
So, mitochondria contain their own ribosomes that is known as the mito ribosome which synthesize a handful of proteins all essential for the biogenesis of the oxidative phosphorylation that is this electron transport chain.
03:15
So, here our right answer would be option a.
03:18
Yes.
03:19
Then in the next question it says which of the following tissue type responds to a hormonal signal that is triggered by the high glucose level by placing additional glute 1 or 4 into the cell membrane.
03:33
So, it is the liver where in the glycogen should be stored.
03:39
So, basically this here is activated so that there is more production of the glycogen if the glucose is increased...
