What would be the potential result of dispensing two drugs that are both weak acids and are hydrophobic? Question 31Select one: a. Easy elimination of each drug because they are hydrophobic b. Drug interaction c. Easy ionization of each drug d. Drug hypersensitivity
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For a weakly acidic drug of pKa = 4, the INCORRECT statement regarding the effects of solution pH on ionization, solubility, and apparent partition coefficient is: a. With increasing the solution pH > 4, the percentage of ionized form of the drug is increased b. With increasing the solution pH > 4, the solubility of the drug is increased. c. With increasing the solution pH > 4, the apparent partition coefficient is decreased. d. With increasing the solution pH > 4, the intrinsic solubility of the drug is increased.
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