When the glomerular transport maximum for a substance such as blood glucose exceeded and its renal threshold has been reached, the substance will: ◯ Reabsorb quickly ◯ Spill into the urine ◯ Countertransport sodium ◻ Attach to protein carriers
Added by Edward L.
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What will happen to the tubular reabsorption of "glucose" when the filtrate contains a greater number of glucose molecules than carriers (transporters)? And then what will happen to the urine?
Adi S.
Glucose is primarily reabsorbed at the kidney by transport using proteins:
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In people with diabetes: High concentrations of glucose completely block SGLT-mediated uptake of glucose, causing glucose to appear in the urine. The transport maximum of glucose uptake across the apical membrane is reached, and the excess glucose is not reabsorbed. The uptake of glucose by SGLT expressed in the cells of the collecting duct is saturated. The high glucose concentration saturates glucose exit across the basolateral membrane.
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