Question

Which of the following is an important step in clot formation? Fibrin monomers spontaneously assemble into ordered fibrous arrays called fibrinopeptides. Upon cleavage with thrombin the exposed ends or "knobs" of the α subunits fit into the holes on the γ subunits of another monomer to form a protofibril. Transglutaminase cleaves four arginine–glycine peptide bonds in the central globular region of fibrinogen to form a fibrin monomer. This cross-linking reaction is catalyzed by transglutaminase (factor XIIIα), which itself is activated from the protransglutaminase form by trypsin.

Name: which of the following is an important step in clot formation fibrin monomers spontaneously assemble into ordered fibrous arrays called fibrinopeptides upon cleavage with thrombin the expose 93563
Uploaded: 2022-06-20T08:10:29-08:00
Duration: 2 min 2 s
Channel: Madhur L
Description: which of the following is an important step in clot formation fibrin monomers spontaneously assemble into ordered fibrous arrays called fibrinopeptides upon cleavage with thrombin the expose 93563

          Which of the following is an important step in clot formation?
Fibrin monomers spontaneously assemble into ordered fibrous arrays called fibrinopeptides.
Upon cleavage with thrombin the exposed ends or "knobs" of the α subunits fit into the holes on the γ subunits of another monomer to form a protofibril.
Transglutaminase cleaves four arginine–glycine peptide bonds in the central globular region of fibrinogen to form a fibrin monomer.
This cross-linking reaction is catalyzed by transglutaminase (factor XIIIα), which itself is activated from the protransglutaminase form by trypsin.

Added by Chad H.

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