Which rationale is correct regarding administration of Rho(D) immune globulin to the mother immediately after delivery after review of the blood test results of a postpartum patient and the neonate? O The neonate and the mother are Rh positive. O The neonate and the mother are Rh negative. O The neonate is Rh positive, and the mother is Rh negative. O The neonate is Rh negative, and the mother is Rh positive. Confident Not Sure
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Rho(D) immune globulin (also known as RhoGAM) is administered to Rh-negative mothers to prevent the formation of antibodies against Rh-positive fetal red blood cells. This is crucial to prevent hemolytic disease of the newborn in subsequent pregnancies. Show moreā¦
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B.W. was seen by her OB-GYN at 10 weeks of gestation with her first pregnancy. Results of her prenatal workup indicate she is group O, D-negative with a negative antibody screen. Repeat testing at 28 weeks continues to indicate a negative antibody screen, and she is given 300 μg of RhIG. The pregnancy proceeds normally, and she delivers a 7 lb 2 oz boy at 39 weeks of gestation. Results of cord blood tests are as follows: Anti-A: 3+ Anti-B: 0 Anti-D: 0 Weak D: 1+ Weak D control: 1+ DAT: 1+ Mother's Sample Screen cells: Weak positive Infant hemoglobin is 17.3 g/dL, and bilirubin is 0.6 mg/dL. 1. Does this infant have HDFN? If so, what is the most probable cause? 2. What could be causing the positive screen result? How would you confirm? An elution is performed. The eluate is tested against Aā, B, and O reagent red cells, incubated at 37° C, and tested at the AHG phase: Eluate (Aā): 1+ Eluate (B): 1+ Eluate (O): Negative 3. What do these results indicate? 4. What type of treatment would be recommended for this infant? 5. Is B.W. a candidate for postpartum RhIG? If so, are any additional tests necessary? A fetal screen performed on B.W. yields a positive result. 6. What test needs to be performed and why? A Kleihauer-Betke stain is performed on B.W.'s postpartum specimen to quantify the amount of FMH. There were 19 fetal cells counted in a total of 2000 cells. 7. How many doses of RhIG should B.W. receive?
Breanna O.
The Rhesus factor blood group in humans is determined by an autosomal allele, where Rhesus positive (Rh+) is completely dominant over Rhesus negative (Rh- ). If a Rhesus negative women is carrying a child who is Rhesus positive, an injection of Rh immune globulin is often administered to prevent the female from producing Rh antibodies during pregnancy. The ABO blood group assorts independently of the Rhesus system. A woman has blood type AB negative (Rhesus negative). A man has blood type O and is heterozygous Rhesus positive. a. Indicate all the possible blood types of their children and the probability of each. (2 marks) b. What is the probability a child will be Rhesus positive (and therefore, the woman may require Rh injections during her pregnancy)? (1 mark)
Md.Daniyal A.
A 30-year-old woman has one living child, aged 6. Her child and her husband are Rh positive, and she is Rho(D) and Du negative. She is now in her ninth month of pregnancy and is in the labor room, experiencing frequent contractions. Her Rh antibody test taken earlier in the pregnancy was negative. What immunotherapy is appropriate for this patient? When and how should it be administered?
Sri K.
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