Vitamin C is required for collagen synthesis its deficiency causes scurvy is synthesized by the skin AMB are correct
Added by Blanca R.
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- Vitamin C - Collagen synthesis - Deficiency causing scurvy - Synthesis by the skin - AMB (which likely stands for "All of the above" or "A, M, B") Show more…
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Defective collagen in scurvy is due to insufficient Vitamin C. Vitamin C: A. Is required for the conversion of lysine to hydroxylysine. B. Is not synthesized by most animals. C. Is involved in the hydroxylation of proline residues. D. Inhibits the oxidative degradation of collagen. E. Is required for the formation of cross-links between tropocollagens.
Adi S.
Scurvy and Collagen. Scurvy is a disease that until the nineteenth century was common among sailors and others whose diets were deficient in vitamin $C$ (ascorbic acid). Individuals with scurvy suffer from various disorders, including extensive bruising, hemorrhages, and breakdown of supporting tissues. Ascorbic acid serves as a reducing agent responsible for maintaining the activity of prolyl hydroxylase, the enzyme that catalyzes hydroxylation of proline residues within the collagen triple helix, which is required for helix stability. (a) Based on this information, postulate a role for hydroxyproline in collagen triple helices, and explain the sequence of events leading from a dietary vitamin C deficiency to symptoms such as bruising and breakdown of supporting tissues. (b) Can you guess why sailors are no longer susceptible to scurvy? And why do you think British sailors are called "limeys" to this day?
Sri K.
Q9.Which one of the following statements is correct. The vitamin C synthesis pathway Has been lost in invertebrates Is found in the kidneys of fish Switched from the liver to kidneys in mammals Has been lost in primates and represents a deleterious deletion Is associated with jaundice
Anand J.
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