What are the advantages of using peptides for the design of hydrogels for biomedical applications?
Added by Karabo S.
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Biocompatibility: Peptides are naturally occurring biological molecules, which makes them highly biocompatible. This means they are less likely to cause adverse reactions when used in the human body. Show more…
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Teaching the Peptide Bond Please teach us about the peptide bond. You'll need to go over the resonance structures of the peptide bond and what implications those resonance structures have for the properties of the molecule. List at least 4 different properties of the peptide bond and explain why they have them.
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Peptides on a chip. Large numbers of different peptides can be synthesized in a small area on a solid support. This high-density array can then be probed with a fluorescencelabeled protein to find out which peptides are recognized. The binding of an antibody to an array of 1024 different peptides occupying a total area the size of a thumbnail is shown in the adjoining illustration. How would you synthesize such a peptide array? (Hint: Use light instead of acid to deprotect the terminal amino group in each round of synthesis.) Fluorescence scan of an array of 1024 peptides in a $1.6-\mathrm{cm}^{2}$ area. Each synthesis site is a 400 - $\mu$ m square. A fluorescently labeled monoclonal antibody was added to the array to identify peptides that are recognized. The height and color of each square denote the fluorescence intensity. [nformation from S. P. A. Fodor et al., Science $251(1991): 767 .]$ PICTURE CANT COPY
1) What are three uses of peptides in medicinal biotechnology? 2) how does a peptide synthesizer make peptides? 3) how does a DNA synthesizer make oligonucleotides? 4) of what value are oligonucleotides?
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