What factors will increase the rate of the Sn2 reaction shown?
(LG is the leaving group and Nu is the nucleophile)
1. Concentration of substrate 2. polar protic solvent 3. larger nucleophile 4. concentration of nucleophile 5. more substitution at adjacent carbon 6. less basic leaving group
A. All of the above B. 1, 2, 5 C. 1, 3, 4 D. 1, 2, 5, 6 E. 1, 4, 6