What is a sigma factor and, in general, how do they facilitate control of gene expression in bacterial cells? Choose one sigma factor to provide detail regarding its functioning and regulatory activities. You must start a thread before you can read and reply to other threads
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They are a component of the RNA polymerase holoenzyme, which is responsible for synthesizing RNA from a DNA template. Sigma factors play a crucial role in the control of gene expression because they guide the RNA polymerase to specific promoter sequences on the Show more…
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Sigma factors affect gene expression, partly through variation in promoters dependent on the same sigma factor. There are also different sigma factors that act to coordinate gene expression through promoters specific to each sigma. A) How do sigma factor -10 and -35 sequences affect gene expression for genes that depend on the same sigma factor for expression? B) Briefly describe a sigma factor that controls expression of a specific regulon.
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