00:01
Okay this question here says, hydratiform moles are growth of undifferentiated tissues that form within the uterus during an abnormal molar pregnancy.
00:11
These moles are usually made up of xx diploid cells, although some can be xy diploids.
00:18
Surprisingly, all of the dna in the nuclei of the cells in a mole is paternal in origin.
00:24
Most hydratiform moles are benign, but because they sometimes can develop into cancers, these moles should be removed surgically when they are detected.
00:32
The first question is, what kinds of events could lead to the generation of a hydratiform mole? so in this case, you will have, for example, complete fertilization of an empty egg.
00:46
So when you have an egg, this is an egg, that lacks maternal dna, and it is fertilized by a normal sperm, it leads to the formation of a complete hydratiform mole.
01:00
And this results in a complete set of paternal chromosomes, but no maternal contribution.
01:04
Practically, you have here your 23 chromosomes, and once there is fertilization, your zygote is going to have only paternal dna, because the genetic material of the father is going to replicate, and you're going to have 46, but this is only from the father.
01:22
Then another possibility is going to be failure of the egg to eject the nucleus after fertilization...