What is the first step in the process of an action potential...

What is the first step in the process of an action potential triggering muscle contraction? The action potential travels to the interior of the muscle cell via T tubules. Ca2+ binds troponin. The neurotransmitter acetylcholine (Ach) is released into the synaptic cleft. Ca2+ diffuses from the sarcoplasmic reticulum into the cytoplasm of the muscle cell.

Transcript

00:01 Talking about the muscle contraction, muscle contraction, we need to give or tell about the initiation of a muscle contraction beginning with the action potential being arriving at a neuromuscular junction and leading it to muscle fiber shortening.

00:22 So we need to give a detailed account of how an action potential is generated.

00:31 So from the generation of action potential to leading on to the muscle fiber getting shortened, muscle fiber getting shortened.

00:46 So now here we basically follow four main procedures.

00:50 The first one is depolarization, depolarization and calcium ion balance or calcium ion release, calcium ion release.

01:09 So in this first step that is depolarization and calcium ion release, we basically see that here there is an action potential generated which triggers the release of acetylcholine into the motor end plate.

01:25 So acetylcholine, acetylcholine, it reaches the motor end plate and this initiates the depolarization within the sarcolemma that is spread through the muscle fiber via the t -tubules.

01:41 So it is done via the t -tubules and then this depolarization causes the sarcoplasmic reticulum to release the calcium ions that plays an important role in initiating the muscular contraction.

01:55 Then your next step is actin and myosin cross bridge.

02:00 So now the actin and myosin that are the structural components of the muscle, they form a cross bridge.

02:09 So they form a cross bridge.

02:12 Now here what happens, on the actin, the binding sites for the myosin are present...

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