00:01
In order to answer this question, let's talk about inheritance.
00:03
If you have a pedigree, okay, and you don't know the inheritance pattern, and we have to determine this inheritance pattern, okay? so first, can this pedigree be a dominant disease? and the answer is no, it is not a dominant because remember that, for example, if this female has a disease, okay, or a specific trait.
00:24
So it means that she has the mutant or the specific allele for that trait.
00:30
Okay, let's talk about disease because.
00:31
It is easier to understand.
00:33
So this woman has a disease that is an inherited disease.
00:37
So it means that she has the defective allele, at least one of the defective adiles, okay? so it means that this allele came from at least one of the parents.
00:47
But as you can see here, both parents are healthy.
00:50
So it means that at least one of the parents is a caguer, and you only have caggers in recessive disorders.
00:57
Now, and the disease be ex -linked recessive, and the answer is not because if it is excellent recessive, then this woman would be like this, homocygose.
01:06
And remember that a person in here is one allele from his parents.
01:10
So in this case, one recessive is coming from the mother.
01:14
And the mother can be a carger, so up to here everything is fine.
01:17
But the second ex -recessive philil should come from the father.
01:21
But if the father has a recessive -fahil, he would be like this.
01:24
And this is the genotype for a man with a disease.
01:31
This man does not have a disease, so it does not fit, and hence this is an autopsomal recessive disorder.
01:37
In this autosomal recessive disorder we're going to use the following nomenclature.
01:41
This is the homozygos dominion and the heterozygot are healthy, while the homozygous recessive are going to be affected.
01:55
So let's start.
01:58
All of these circles here that are shaded and also squares are going to be, they are going to be homozygotes so you have here homozygos decessive, homozygos decessive, homozygos decessive, homozygos recessive.
02:16
Now let's see at this woman here, as i told you, one person in here is one from each parent...